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Cat. No. Product Name Target Signaling Pathways
T77698 hCYP3A4 Fluorogenic substrate 1

Others Others
hCYP3A4 Fluorogenic substrate 1 是邻苯二甲酰亚胺衍生物,对 COX 表现出低活性。
T37021 Enteropeptidase Fluorogenic Substrate

Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage. Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ac...
T35880 Renin Fluorogenic Substrate

The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using an excitation wavelength of 340 nm and emission wavelengths of 485-510 nm.
T37022 Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)

Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ...
T83759 MMP-3 Fluorogenic Substrate TFA

Mca-RPKPVE-Nval-WR-K(Dnp)-NH2,Matrix Metalloproteinase-3 Fluorogenic Substrate,Stromelysin-1 Fluorogenic Substrate

MMP-3 fluorogenic substrate 是一种针对基质金属蛋白酶-3(MMP-3)的荧光底物。当被MMP-3切割后,7-甲氧基香豆素-4-乙酰基(Mca)会释放并且其荧光可用于量化MMP-3活性。Mca的激发/发射峰值分别为328/420 nm。
T78625 Z-Ala-Arg-Arg-AMC

Z-ARR-AMC,Fluorogenic Proteasome Substrate

Proteasome Proteases/Proteasome; Ubiquitination
Z-Ala-Arg-Arg-AMC (FluorogenicProteasomeSubstrate) 作为荧光底物,专用于检测蛋白酶体中的胰蛋白酶样活性。
T18888 4-Methylumbelliferyl phosphate

4-甲基伞形酮磷酸酯,4-MUP

Others Others
4-Methylumbelliferyl phosphate (4-MUP) 是碱性磷酸酶的荧光底物。
TD0081 EDANS

EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],EDANS酸,1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht

Others Others
EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) 是新型的淬灭荧光底物 (fluorogenic substrate),可利用共振能量转移,分析逆转录病毒蛋白酶。
T37571 4-Methylumbelliferyl-β-D-Glucopyranoside

MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc,4-甲基伞形酮酰-Β-D-吡喃葡糖酸苷

Others Others
4-Methylumbelliferyl-β-D-Glucopyranoside (4-MU-GLU) 是β-glucosidase 的荧光底物,可用于β-glucosidase 活性的测定,期间释放出高荧光的 4-methylumbelliferyl (4-MU),发射波长为 445-454 nm。4-MU 激发波长值与 pH 值有关,在 pH 值为 4.6、7.4 和 10.4 时分别为 330、370 和 385 nm。
T64341 H-β-Ala-AMC TFA

Others Others
H-β-Ala-AMC TFA 是氨基肽酶的底物之一。
TP1326 Ac-DEVD-AFC

Others Others
Ac-DEVD-AFC 是荧光底物 (λex=400 nm, λem=530 nm)。
T18912 ADHP

10-乙酰基-3,7-二羟基吩嗪,10-Acetyl-3,7-dihydroxyphenoxazine

Others Others
ADHP (10-Acetyl-3,7-dihydroxyphenoxazine) 是荧光过氧化物酶底物,其λex=530 nm,λem=590 nm。
T37504L Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)

Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)

Cathepsin D and E FRET Substrate acetate 是组织蛋白酶 D 和 E 的荧光底物,但不适用于 B、H 或 L。Cathepsin D and E FRET Substrate acetate 可用于组织蛋白酶 D 和 E 研究的机理研究。
T8556 Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)

Z-Gly-Gly-Arg-AMC TFA

Others Others
Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base) 是一种凝血酶特异性荧光底物,用于检测 PRP 和贫血小板血浆 (PPP) 中的凝血酶生成。
T37192 4-Methylumbelliferyl-α-D-Galactopyranoside

4MU-α-Gal

Others Others
4-Methylumbelliferyl-α-D-Galactopyranoside (4MU-α-Gal) (4-MU-α-Gal)是α-半乳糖苷酶的荧光底物。除了用于表征新的α-半乳糖苷酶外,4-MU-α-Gal 还用于评估与法布里病相关的α-半乳糖糖苷酶活性的缺乏。
T33795 OMFP

3-OMFP

OMFP is a fluorogenic substrate for phosphatase.
T18993 Fluorescein di(β-D-galactopyranoside)

FDG

Others Others
Fluorescein di(β-D-galactopyranoside) is a fluorogenic substrate for β-galactosidase (λem=535 nm, λex=485 nm).
T18937 CUG

3-Carboxyumbelliferyl-β-D-galactopyranoside

Others Others
CUG is a fluorogenic substrate (λex=386, λem=445 nm, ε=32K).
T19047 PL553

Others Others
PL553 is a specific and high-affinity fluorogenic substrate of Leukotriene A4 hydrolase (λmax: 210 nm; λem: 410 nm).
T29485 7-Lysylalanyl-4-methylcoumarinamide

7-Lysylalanyl-4-methylcoumarinamide is a Fluorogenic substrate for dipeptidyl aminopeptidase.
T39729 HIV Protease Substrate 1

HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
TP1099 M-2420

Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl

M-2420 is a fluorogenic substrate designed specifically for the β-secretase site found in the Swedish mutation of the amyloid precursor protein (APP).
TP1799 Z-Gly-Gly-Arg-AMC

Z-Gly-Gly-Arg-AMC is a specific fluorogenic substrate utilized for assessing thrombin generation in Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP), with a particular focus on thrombin activity.
T28405 Phe-Pro-Arg-PABA-Resorufin

Phe-Pro-Arg-PABA-Resorufin is a Chromogenic and fluorogenic peptide substrate for the highly sensitive detection of proteases in biological matrices. The substrate is also applicable to the sensitive detection of the thrombin inhibitor dabigatran in human
TP1368 Ac-Leu-Arg-AMC

Ac-Leu-Arg-AMC is a fluorogenic peptide substrate.
T80107 Tos-Gly-Pro-Lys-AMC

Tos-Gly-Pro-Lys-AMC为特异性类胰蛋白酶荧光肽底物,通常用于酶活性检测。
T80110 Ac-VRPR-AMC

Caspase Apoptosis; Proteases/Proteasome
Ac-VRPR-AMC为特异性荧光metacaspase底物,常用以测定metacaspase活性。
T76268 Mca-VDQVDGW-Lys(Dnp)-NH2

Mca-VDQVDGW-Lys(Dnp)-NH2 是 caspase-7 的荧光底物。可用于定量 caspase-7 活性。
T36686 Ac-Arg-Gly-Lys(Ac)-AMC

Ac-RGK(Ac)-AMC, fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin.
T36363 Dnp-RPLALWRS (trifluoroacetate salt)

Dnp-RPLALWRS is a fluorogenic substrate for matrix metalloproteinase-7 (MMP-7). The activity of MMP-7 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
T40384 Mca-Ala-Pro-Lys(Dnp)-OH

Mca-Ala-Pro-Lys(Dnp)-OH, a specific quenched fluorogenic substrate for ACE2, enables the detection of ACE2 activity in various tissues including urinary, heart, and lung.
T75107 CrBKA

CrBKA 是SIRT6的弱活性荧光小分子底物。
T76074 HIV Protease Substrate 1 TFA

HIV ProteaseSubstrate 1 TFA 是一种外源性 HIV 蛋白酶底物,可用于研究 HIV 蛋白酶的酶活性。
TP2169 Boc-Leu-Gly-Arg-AMC

Others Others
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate of the convertases used in enzymatic assays.
T76606 Ac-Trp-Glu-His-Asp-AMC

Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) 是caspase-1的有效荧光底物。
T76607 Boc-Arg-Val-Arg-Arg-AMC hydrochloride

Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) 是一种合成的荧光底物,可被furin 蛋白酶有效裂解。
T80545 Ac-VEID-AFC

Caspase Apoptosis; Proteases/Proteasome
Ac-VEID-AFC为caspase-6专一的荧光底物,适用于测定caspase 6活性。
T36334 Z-VAD-AMC (acetate)

Z-VAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T38378 Dnp-PLAYWAR (trifluoroacetate salt)

Dnp-PLAYWAR is a fluorogenic substrate for matrix metalloproteinase-8 (MMP-8) and MMP-26. The activity of MMP-8 and MMP-26 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis that removes the N-terminal dinitrophenol (Dnp) group.
TP1129 Boc-Ile-Glu-Gly-Arg-AMC

IEGR-AMC

Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC), a specific, highly fluorogenic substrate for clotting enzyme factor Xa (coagulation factor Xa). Boc-IEGR-AMC is also hydrolyzed by acrosin from the ascidian Halocynthia roretzi.
T80211 Ac-KQL-AMC

Ac-KQL-AMC是量化蛋白酶体样活性的荧光底物,其被裂解时释放可检测的荧光信号。
T80112 Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2

HIV Protease Microbiology/Virology; Proteases/Proteasome
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 是一种用于检测HIV-1蛋白酶活性的荧光底物。
T76090 Mca-YVADAP-Lys(Dnp)-OH

Mca-YVADAP-Lys(Dnp)-OH 是caspase-1和血管紧张素转换酶 2 (ACE2) 的荧光底物。
T83181 Ac-IETD-AMC

Ac-IETD-AMC为乙酰基(Ac)修饰的荧光caspase-8/颗粒酶B底物,常用于检测caspase-8活性。
T40837 7-Acetoxy-1-methylquinolinium iodide

7-乙酰氧基-1-甲基喹啉溴化物,AMQI

7-Acetoxy-1-methylquinolinium iodide (AMQI) serves as a fluorogenic substrate for cholinesterase, with excitation (Ex) occurring at 320 nm and emission (Em) at 410 nm. In the fluorometric flow system, the hydrolysis of this compound is employed for the detection and identification of inhibitors.
T36354 Suc-YVAD-AMC (acetate)

Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T37025 Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
T41004 Coumberone

Coumberone is a metabolic fluorogenic probe and isoform-selective substrate for all AKR1C isoforms. It can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone is a valuable tool for researching AKR1C.
T36360 Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2

Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. Upon cleavage by MMP-1 or MMP-9, N-methylanthranilic acid (Nma) is unquenched and its fluorescence can be used to quantify MMP activity. Nma displays excitation/emission spectra of 340/440 nm, respectively.
T78386 4-Methylumbelliferyl oleate

4-Methylumbelliferyl oleate是酸性及碱性脂肪酶的荧光底物,能被脂肪酶裂解,从而释放出4-Methylumbelliferyl(Ex/Em=320/450 nm)。

化合物

hCYP3A4 Fluorogenic substrate 1
Cat.No: T77698
Synonym:
Target: Others
Enteropeptidase Fluorogenic Substrate
Cat.No: T37021
Synonym:
Target:
Renin Fluorogenic Substrate
Cat.No: T35880
Synonym:
Target:
Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)
Cat.No: T37022
Synonym:
Target:
MMP-3 Fluorogenic Substrate TFA
Cat.No: T83759
Synonym: Mca-RPKPVE-Nval-WR-K(Dnp)-NH2,Matrix Metalloproteinase-3 Fluorogenic Substrate,Stromelysin-1 Fluorogenic Substrate
Target:
Z-Ala-Arg-Arg-AMC
Cat.No: T78625
Synonym: Z-ARR-AMC,Fluorogenic Proteasome Substrate
Target: Proteasome
4-Methylumbelliferyl phosphate
Cat.No: T18888
Synonym: 4-甲基伞形酮磷酸酯,4-MUP
Target: Others
EDANS
Cat.No: TD0081
Synonym: EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],EDANS酸,1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht
Target: Others
4-Methylumbelliferyl-β-D-Glucopyranoside
Cat.No: T37571
Synonym: MU-GLU,4-MUG,4-MU-GLU,4-MU-β-Gluc,4-甲基伞形酮酰-Β-D-吡喃葡糖酸苷
Target: Others
H-β-Ala-AMC TFA
Cat.No: T64341
Synonym:
Target: Others
Ac-DEVD-AFC
Cat.No: TP1326
Synonym:
Target: Others
ADHP
Cat.No: T18912
Synonym: 10-乙酰基-3,7-二羟基吩嗪,10-Acetyl-3,7-dihydroxyphenoxazine
Target: Others
Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Cat.No: T37504L
Synonym: Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Target:
Z-Gly-Gly-Arg-AMC TFA (66216-78-2 free base)
Cat.No: T8556
Synonym: Z-Gly-Gly-Arg-AMC TFA
Target: Others
4-Methylumbelliferyl-α-D-Galactopyranoside
Cat.No: T37192
Synonym: 4MU-α-Gal
Target: Others
OMFP
Cat.No: T33795
Synonym: 3-OMFP
Target:
Fluorescein di(β-D-galactopyranoside)
Cat.No: T18993
Synonym: FDG
Target: Others
CUG
Cat.No: T18937
Synonym: 3-Carboxyumbelliferyl-β-D-galactopyranoside
Target: Others
PL553
Cat.No: T19047
Synonym:
Target: Others
7-Lysylalanyl-4-methylcoumarinamide
Cat.No: T29485
Synonym:
Target:
HIV Protease Substrate 1
Cat.No: T39729
Synonym:
Target:
M-2420
Cat.No: TP1099
Synonym: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl
Target:
Z-Gly-Gly-Arg-AMC
Cat.No: TP1799
Synonym:
Target:
Phe-Pro-Arg-PABA-Resorufin
Cat.No: T28405
Synonym:
Target:
Ac-Leu-Arg-AMC
Cat.No: TP1368
Synonym:
Target:
Tos-Gly-Pro-Lys-AMC
Cat.No: T80107
Synonym:
Target:
Ac-VRPR-AMC
Cat.No: T80110
Synonym:
Target: Caspase
Mca-VDQVDGW-Lys(Dnp)-NH2
Cat.No: T76268
Synonym:
Target:
Ac-Arg-Gly-Lys(Ac)-AMC
Cat.No: T36686
Synonym:
Target:
Dnp-RPLALWRS (trifluoroacetate salt)
Cat.No: T36363
Synonym:
Target:
Mca-Ala-Pro-Lys(Dnp)-OH
Cat.No: T40384
Synonym:
Target:
CrBKA
Cat.No: T75107
Synonym:
Target:
HIV Protease Substrate 1 TFA
Cat.No: T76074
Synonym:
Target:
Boc-Leu-Gly-Arg-AMC
Cat.No: TP2169
Synonym:
Target: Others
Ac-Trp-Glu-His-Asp-AMC
Cat.No: T76606
Synonym:
Target:
Boc-Arg-Val-Arg-Arg-AMC hydrochloride
Cat.No: T76607
Synonym:
Target:
Ac-VEID-AFC
Cat.No: T80545
Synonym:
Target: Caspase
Z-VAD-AMC (acetate)
Cat.No: T36334
Synonym:
Target:
Dnp-PLAYWAR (trifluoroacetate salt)
Cat.No: T38378
Synonym:
Target:
Boc-Ile-Glu-Gly-Arg-AMC
Cat.No: TP1129
Synonym: IEGR-AMC
Target:
Ac-KQL-AMC
Cat.No: T80211
Synonym:
Target:
Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2
Cat.No: T80112
Synonym:
Target: HIV Protease
Mca-YVADAP-Lys(Dnp)-OH
Cat.No: T76090
Synonym:
Target:
Ac-IETD-AMC
Cat.No: T83181
Synonym:
Target:
7-Acetoxy-1-methylquinolinium iodide
Cat.No: T40837
Synonym: 7-乙酰氧基-1-甲基喹啉溴化物,AMQI
Target:
Suc-YVAD-AMC (acetate)
Cat.No: T36354
Synonym:
Target:
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2
Cat.No: T37025
Synonym: Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2
Target:
Coumberone
Cat.No: T41004
Synonym:
Target:
Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
Cat.No: T36360
Synonym: Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
Target:
4-Methylumbelliferyl oleate
Cat.No: T78386
Synonym:
Target:
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